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Search Results for " muscarinic acetylcholine receptor m5 "

Targets

7

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T8219 VU0238441 AChR
VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.
T12679 (Rac)-VU 6008667 Others , AChR
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) with IC50 of 1.8 μM and pIC50 of 5.75, has high CNS penetration.
T8007 VU 0238429 SCR-1481B1,VU0238429 AChR
VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).
T1475 Fesoterodine fumarate Toviaz,SPM 907 AChR
Fesoterodine fumarate (Toviaz) is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo...
T23763 Atropine Oxide NSC 72861,NSC72861,NSC-72861
Atropine Oxide is a derivative of Atropine. Atropine is a competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5. Atropine is a medication to treat certain types of nerve agents and ...
T37728 Methoctramine (hydrate)
Methoctramine is a selective antagonist of M2 muscarinic acetylcholine receptors (IC50 = 6.1 nM in CHO-K1 cell membranes).[1] It is selective for M2 over M1, M3, M4, and M5 receptors (IC50s = 92, 770, 260, and 217 nM, re...
T69232 Atropine Oxide Hydrochloride
Atropine Oxide is a derivative of Atropine. Atropine is a medication to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate and to decrease saliva production during surger...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01717 CHRM5 Protein, Human, Recombinant (His) Human E. coli
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. ...
TargetMol