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Cat No. | Product Name | Synonyms | Targets |
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T8219 | VU0238441 | AChR | |
VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM. | |||
T12679 | (Rac)-VU 6008667 | Others , AChR | |
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) with IC50 of 1.8 μM and pIC50 of 5.75, has high CNS penetration. | |||
T8007 | VU 0238429 | SCR-1481B1,VU0238429 | AChR |
VU 0238429 (SCR-1481B1) is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM). | |||
T1475 | Fesoterodine fumarate | Toviaz,SPM 907 | AChR |
Fesoterodine fumarate (Toviaz) is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo... | |||
T23763 | Atropine Oxide | NSC 72861,NSC72861,NSC-72861 | |
Atropine Oxide is a derivative of Atropine. Atropine is a competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5. Atropine is a medication to treat certain types of nerve agents and ... | |||
T37728 | Methoctramine (hydrate) | ||
Methoctramine is a selective antagonist of M2 muscarinic acetylcholine receptors (IC50 = 6.1 nM in CHO-K1 cell membranes).[1] It is selective for M2 over M1, M3, M4, and M5 receptors (IC50s = 92, 770, 260, and 217 nM, re... | |||
T69232 | Atropine Oxide Hydrochloride | ||
Atropine Oxide is a derivative of Atropine. Atropine is a medication to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate and to decrease saliva production during surger... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01717 | CHRM5 Protein, Human, Recombinant (His) | Human | E. coli |
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. ... |